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Brains Reactions to Salvia Researched

In a recently made study scientist researched the distribution of salvinorin A in the brain. Salvinorin A is the active ingredient found in Salvia divinorum, known as the potent hallucinogenic herb. The research was made in the U.S. Department of Energy, Brookhaven National Laboratory.

Hooker and fellow researchers used positron emission tomography, or PET scanning, to watch the distribution of salvinorin A in the brains of anesthetized primates.

The peak concentration of salvinorin A was found in 40 seconds after the start of the test and after 16 minutes the drug had basically disappeared. This means salvia affects the brain nearly ten times faster than for example cocaine. The scientists believe the reason for salvia’s popularity could be its fast onset and short duration.

Based on their results and published data from human use, the scientists estimate that just 10 micrograms of salvia in the brain is needed to cause psychoactive effects in humans.

High concentrations of the drug were found near the parts of the brain which cope with motor function and vision. That explainsthe effects on human users on a salvia trip. Chemist Jacob Hooker says the drug targets a receptor that is known to modulate pain and could have an important therapical use. The researchers plan to make further studies related to salvia’s potential.

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